Iniparib
Catalog No: 16071103
CAS Number: 160003-66-7
Purity: 98% by HPLC
Iniparib, also known as BSI-201, is a small-molecule prodrug inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase-1 (PARP-1) with potential chemosensitizing, radiosensitizing and antineoplastic activities. In vivo, PARP-1 inhibitor BSI-201 is converted to the active drug, which selectively binds to PARP-1 and inhibits PARP-1- mediated DNA repair. Consequently, this agent may enhance the cytotoxicity of DNA-damaging agents and reverse tumor cell resistance to chemotherapy and radiation therapy. In addition, PARP-1 inhibitor BSI-201 may exhibit direct antineoplastic activity against cancers defective in DNA repair.
For research use only. We do not sell to patients.
Chemical Information
| Name | Iniparib |
|---|---|
| Iupac Chemical Name | 4-iodo-3-nitrobenzamide |
| Synonyms | BSI-201; BSI201 |
| Molecular Formula | C7H5IN2O3 |
| Molecular Weight | 292.03067 |
| Smile | IC1=C(C=C(C(=O)N)C=C1)[N+](=O)[O-] |
| InChiKey | MDOJTZQKHMAPBK-UHFFFAOYSA-N |
| InChi | InChI=1S/C7H5IN2O3/c8-5-2-1-4(7(9)11)3-6(5)10(12)13/h1-3H,(H2,9,11) |
| CAS Number | 160003-66-7 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% by HPLC |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
