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JH-VIII-157-02

Catalog No: 62103
CAS Number: 1639422-97-1
Purity: 98% by HPLC 

JH-VIII-157-02, a structural analogue of alectinib, is potent against the G1202R mutant as well as a variety of other frequently observed mutants. In addition, it is capable of penetrating the CNS of mice following oral dosing. 

For research use only. We do not sell to patients.

Chemical Information

NameJH-VIII-157-02
Iupac Chemical Name1H-Pyrazole-1-acetamide, 4-(3-cyano-9-ethyl-6,11-dihydro-6,6-dimethyl-11-oxo-5H-benzo[b]carbazol-8-yl)-N,N-dimethyl- 
SynonymsJH-VIII-157-02;CAS#1639422-97-1 
Molecular FormulaC28H27N5O2 
Molecular Weight465.55 
SmileO=C(N(C)C)CN1N=CC(C2=C(CC)C=C3C(C(C)(C)C(NC4=C5C=CC(C#N)=C4)=C5C3=O)=C2)=C1
InChiKeyIDGNCVHQDDOPND-UHFFFAOYSA-N
InChiInChI=1S/C28H27N5O2/c1-6-17-10-21-22(11-20(17)18-13-30-33(14-18)15-24(34)32(4)5)28(2,3)27-25(26(21)35)19-8-7-16(12-29)9-23(19)31-27/h7-11,13-14,31H,6,15H2,1-5H3
CAS Number1639422-97-1
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Ordering Information

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FormulationSolid powder 
Purity98% by HPLC 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

62103 - JH-VIII-157-02 | CAS 1639422-97-1

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