JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents depression-associated behaviors induced by chronic social defeat stress.
For research use only. We do not sell to patients.
Name | JHU-083 |
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Iupac Chemical Name | ethyl (S)-2-((S)-2-amino-4-methylpentanamido)-6-diazo-5-oxohexanoate |
Synonyms | JHU-083 ; JHU 083 ; JHU083 |
Molecular Formula | C14H24N4O4 |
Molecular Weight | 312.37 |
Smile | [N-]=[N+]=CC(CC[C@@H](C(OCC)=O)NC([C@H](CC(C)C)N)=O)=O |
InChiKey | YZRCHOFKIPHQBW-RYUDHWBXSA-N |
InChi | InChI=1S/C14H24N4O4/c1-4-22-14(21)12(6-5-10(19)8-17-16)18-13(20)11(15)7-9(2)3/h8-9,11-12H,4-7,15H2,1-3H3,(H,18,20)/t11-,12-/m0/s1 |
CAS Number | 1998725-11-3 |
Related CAS | 1998725-11-3 |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Off-white solid |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |