JNJ-42041935 is a potent (pKi = 7.3-7.9), 2-oxoglutarate competitive, reversible, and selective inhibitor of PHD enzymes.
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Chemical Information
Name | JNJ-42041935 |
Iupac Chemical Name | 1-[6-chloro-5-(trifluoromethoxy)-1H-benzimidazol-2-yl]pyrazole-4-carboxylic acid |
Synonyms | JNJ 42041935; JNJ42041935 |
Molecular Formula | C12H6ClF3N4O3 |
Molecular Weight | 346.65 |
Smile | C1=C2C(=CC(=C1Cl)OC(F)(F)F)N=C(N2)N3C=C(C=N3)C(=O)O |
InChiKey | FXHHASJVTYRJHH-UHFFFAOYSA-N |
InChi | InChI=1S/C12H6ClF3N4O3/c13-6-1-7-8(2-9(6)23-12(14,15)16)19-11(18-7)20-4-5(3-17-20)10(21)22/h1-4H,(H,18,19)(H,21,22) |
CAS Number | 1193383-09-3 |
Related CAS | |
Ordering Information
Packaging | Price | Availability | Purity | Shipping Time |
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Formulation | Solid powder |
Purity | 98% |
Storage | -20 ºC for 3 years |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
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Mechanism | |
Cell study | |
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Clinical study | |