JTE-051 is a novel inhibitor of interleukin-2-inducible T cell kinase (ITK), suppressing the signal to activate T cells related to immune response.
For research use only. We do not sell to patients.
Name | JTE-051 |
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Iupac Chemical Name | (S)-N-(2-(6,6-dimethyl-4,5,6,7-tetrahydro-1H-indazol-3-yl)-1H-indol-6-yl)-N-methyl-2-morpholinopropanamide |
Synonyms | JTE-051; JTE051; JTE 051; |
Molecular Formula | C25H33N5O2 |
Molecular Weight | 435.56 |
Smile | C[C@H](N1CCOCC1)C(N(C2=CC3=C(C=C2)C=C(C4=NNC5=C4CCC(C)(C)C5)N3)C)=O |
InChiKey | ZZZXGCPVQQOASC-INIZCTEOSA-N |
InChi | InChI=1S/C25H33N5O2/c1-16(30-9-11-32-12-10-30)24(31)29(4)18-6-5-17-13-21(26-20(17)14-18)23-19-7-8-25(2,3)15-22(19)27-28-23/h5-6,13-14,16,26H,7-12,15H2,1-4H3,(H,27,28)/t16-/m0/s1 |
CAS Number | 1309784-09-5 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
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Purity | 98% Min. |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |