JWH-133
Catalog No: 6111109
CAS Number: 259869-55-1
Purity: 98%
JWH 133 is a potent CB2 selective agonist with Ki of 3.4 nM, 200-fold selective over CB1 receptors.
JWH-133 inhibits IL-12p40 production and enhances IL-10 release by activated macrophages through a CB2 receptor-mediated pathway. a widely used experimental in vitro model to study mechanisms of toxicity and protection in nigral dopaminergic neurons. JWH-133 (10-40 M) induced a concentration-dependent decrease of SH-SY5Y cell viability and proliferation rate.
For research use only. We do not sell to patients.
Chemical Information
| Name | JWH-133 |
|---|---|
| Iupac Chemical Name | JWH-133 |
| Synonyms | JWH133; JWH 133 |
| Molecular Formula | C22H32O |
| Molecular Weight | 312.49 |
| Smile | CCCC(C)(C)c1ccc2c(c1)OC([C@H]3[C@H]2CC(=CC3)C)(C)C |
| InChiKey | YSBFLLZNALVODA-RBUKOAKNSA-N |
| InChi | InChI=1S/C22H32O/c1-7-12-21(3,4)16-9-10-17-18-13-15(2)8-11-19(18)22(5,6)23-20(17)14-16/h8-10,14,18-19H,7,11-13H2,1-6H3/t18-,19+/m0/s1 |
| CAS Number | 259869-55-1 |
| MDL | MFCD06795847 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
