KGP-94
Catalog No: 3291806
CAS Number: 1131456-28-4
Purity: >98%
KGP94 is a reversible, time-dependent and competitive inhibitor of human cathepsin L. ► KGP94 inhibits the activity of cathepsin L toward human type I collagen. ► KGP94 significantly impedes both migration and invasion of MDA-MB-231 human breast cancer cells. ► Molecular modeling places the thiocarbonyl of KGP94 in proximity to the active site Cys25. ► Significant growth retardation of C3H mouse mammary carcinomas is achieved with KGP94 treatment.
For research use only. We do not sell to patients.
Chemical Information
| Name | KGP-94 |
|---|---|
| Iupac Chemical Name | 2-((3-bromophenyl)(3-hydroxyphenyl)methylene)hydrazinecarbothioamide |
| Synonyms | KGP-94;KGP94;KGP 94 |
| Molecular Formula | C14H12BrN3OS |
| Molecular Weight | 350.23 |
| Smile | OC1=CC(/C(C2=CC=CC(Br)=C2)=N\NC(N)=S)=CC=C1 |
| InChiKey | ZDBKSZKTCPOBFR-LGMDPLHJSA-N |
| InChi | InChI=1S/C14H12BrN3OS/c15-11-5-1-3-9(7-11)13(17-18-14(16)20)10-4-2-6-12(19)8-10/h1-8,19H,(H3,16,18,20)/b17-13- |
| CAS Number | 1131456-28-4 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | >98% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, acetone, not in water |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
