KH-3
Catalog No: 24143
CAS Number: 1215115-03-9
Purity: 98% Min.
KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC50 value of 0.35 μM.
For research use only. We do not sell to patients.
Chemical Information
| Name | KH-3 |
|---|---|
| Iupac Chemical Name | (E)-3-(5-((4-(tert-butyl)phenyl)sulfonamido)benzo[b]thiophen-2-yl)-N-hydroxyacrylamide |
| Synonyms | KH-3; KH3; KH 3 |
| Molecular Formula | C21H22N2O4S2 |
| Molecular Weight | 430.54 |
| Smile | O=C(NO)/C=C/C1=CC2=CC(NS(=O)(C3=CC=C(C(C)(C)C)C=C3)=O)=CC=C2S1 |
| InChiKey | RIYPLPNXICDUCS-YRNVUSSQSA-N |
| InChi | InChI=1S/C21H22N2O4S2/c1-21(2,3)15-4-8-18(9-5-15)29(26,27)23-16-6-10-19-14(12-16)13-17(28-19)7-11-20(24)22-25/h4-13,23,25H,1-3H3,(H,22,24)/b11-7+ |
| CAS Number | 1215115-03-9 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid |
|---|---|
| Purity | 98% Min. |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Wu X, Gardashova G, Lan L, Han S, Zhong C, Marquez RT, Wei L, Wood S, Roy S, Gowthaman R, Karanicolas J, Gao FP, Dixon DA, Welch DR, Li L, Ji M, Aubé J, Xu L. Targeting the interaction between RNA-binding protein HuR and FOXQ1 suppresses breast cancer invasion and metastasis. Commun Biol. 2020 Apr 24;3(1):193. doi: 10.1038/s42003-020-0933-1. PMID: 32332873; PMCID: PMC7181695.
Chemical Structure
