LDN193189
Catalog No: 52733
CAS Number: 1062368-24-4
Purity: 98%
LDN193189(DM 3189) is a selective BMP signaling inhibitor, inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively, exhibits 200-fold selectivity for BMP versus TGF-
For research use only. We do not sell to patients.
Chemical Information
| Name | LDN193189 |
|---|---|
| Iupac Chemical Name | 4-[6-(4-Piperazin-1-yl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline |
| Synonyms | LDN193189;LDN 193189;LDN-193189 |
| Molecular Formula | C25H22N6 |
| Molecular Weight | 406.48 |
| Smile | N1(CCNCC1)C1=CC=C(C=C1)C=1C=NC=2N(C1)N=CC2C2=CC=NC1=CC=CC=C21 |
| InChiKey | CDOVNWNANFFLFJ-UHFFFAOYSA-N |
| InChi | InChI=1S/C25H22N6/c1-2-4-24-22(3-1)21(9-10-27-24)23-16-29-31-17-19(15-28-25(23)31)18-5-7-20(8-6-18)30-13-11-26-12-14-30/h1-10,15-17,26H,11-14H2 |
| CAS Number | 1062368-24-4 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | DMSO ��4mg/mL; Water ��30mg/mL; Ethanol <1mg/mL |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
