LJH685 is a potent pan-RSK inhibitor with IC50 of 6 nM, 5 nM and 4 nM for RSK1, RSK2, and RSK3, respectively.
For research use only. We do not sell to patients.
Chemical Information
Name | LJH685 |
Iupac Chemical Name | Phenol, 2,6-difluoro-4-[4-[4-(4-methyl-1-piperazinyl)phenyl]-3-pyridinyl]- |
Synonyms | LJH685 |
Molecular Formula | C22H21F2N3O |
Molecular Weight | 381.42 |
Smile | FC1=C(C(=CC(=C1)C=1C=NC=CC1C1=CC=C(C=C1)N1CCN(CC1)C)F)O |
InChiKey | IKUFKDGKRLMXEX-UHFFFAOYSA-N |
InChi | InChI=1S/C22H21F2N3O/c1-26-8-10-27(11-9-26)17-4-2-15(3-5-17)18-6-7-25-14-19(18)16-12-20(23)22(28)21(24)13-16/h2-7,12-14,28H,8-11H2,1H3 |
CAS Number | 1627710-50-2 |
Related CAS | |
Ordering Information
Packaging | Price | Availability | Purity | Shipping Time |
Bulk | | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
Purity | 98% by HPLC |
Storage | -20 ºC for 3 years |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code | |
Targets | |
Mechanism | |
Cell study | |
Animal study | |
Clinical study | |