LJI308 is a potent, and pan-RSK (p90 ribosomal S6 kinase) inhibitor with IC50 of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.
For research use only. We do not sell to patients.
Chemical Information
Name | LJI308 |
Iupac Chemical Name | Phenol, 2,6-difluoro-4-[4-[4-(4-morpholinyl)phenyl]-3-pyridinyl]- |
Synonyms | LJI308 |
Molecular Formula | C21H18F2N2O2 |
Molecular Weight | 368.38 |
Smile | FC1=C(C(=CC(=C1)C=1C=NC=CC1C1=CC=C(C=C1)N1CCOCC1)F)O |
InChiKey | YUYJEQHNWKQNBT-UHFFFAOYSA-N |
InChi | InChI=1S/C21H18F2N2O2/c22-19-11-15(12-20(23)21(19)26)18-13-24-6-5-17(18)14-1-3-16(4-2-14)25-7-9-27-10-8-25/h1-6,11-13,26H,7-10H2 |
CAS Number | 1627709-94-7 |
Related CAS | |
Ordering Information
Packaging | Price | Availability | Purity | Shipping Time |
Bulk | | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
Purity | 98% by HPLC |
Storage | -20 ºC for 3 years |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code | |
Targets | |
Mechanism | |
Cell study | |
Animal study | |
Clinical study | |