LOXO-101 (ARRY-470)

Catalog No: 16123036

CAS Number: 1223403-58-4

Purity: 98%

Larotrectinib, also known as ARRY-470 and LOXO-101, is an orally bioavailable, potent, ATP-competitive inhibitor of TRKA, TRKB,

For research use only. We do not sell to patients.

Name	LOXO-101 (ARRY-470)
Iupac Chemical Name	(S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide
Synonyms	LOXO101;ARRY-470;ARRY470;ARRY 470;larotrectinib
Molecular Formula	C21H22F2N6O2
Molecular Weight	428.44
Smile	FC1=C(C=C(C=C1)F)[C@@H]1N(CCC1)C1=NC=2N(C=C1)N=CC2NC(=O)N2C[C@H](CC2)O
InChiKey	NYNZQNWKBKUAII-KBXCAEBGSA-N
InChi	InChI=1S/C21H22F2N6O2/c22-13-3-4-16(23)15(10-13)18-2-1-7-28(18)19-6-9-29-20(26-19)17(11-24-29)25-21(31)27-8-5-14(30)12-27/h3-4,6,9-11,14,18,30H,1-2,5,7-8,12H2,(H,25,31)/t14-,18+/m0/s1
CAS Number	1223403-58-4
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Formulation	crystalline solid
Purity	98%
Storage	3 years -20℃powder
Solubility	Soluble in DMSO
Handling
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical.
HS Code

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