LP-533401 HCl is an inhibitor of tryptophan hydroxylase-1 (Tph-1), the initial enzyme in gut-derived serotonin (GDS) biosynthesis.
For research use only. We do not sell to patients.
Name | LP-533401 HCl |
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Iupac Chemical Name | 2(S)-Amino-3-(4-{2-amino-6-[2,2,2-trifluoro-1-(3'-fluoro-biphenyl-4-yl)-ethoxy]-pyrimidin-4-yl}-phenyl)-propionic acid Hydrochloride |
Synonyms | LP-533401 HCl; LP 533401 HCl; LP533401 HCl; LP-533401 Hydrochloride; LP 533401 Hydrochloride; LP533401 Hydrochloride; |
Molecular Formula | C27H23ClF4N4O3 |
Molecular Weight | 562.94 |
Smile | O=C(O)[C@@H](N)CC1=CC=C(C2=NC(N)=NC(OC(C3=CC=C(C4=CC=CC(F)=C4)C=C3)C(F)(F)F)=C2)C=C1.[H]Cl |
InChiKey | BHBWZCUMIXCDPM-CHXZROHQSA-N |
InChi | InChI=1S/C27H22F4N4O3.ClH/c28-20-3-1-2-19(13-20)16-8-10-18(11-9-16)24(27(29,30)31)38-23-14-22(34-26(33)35-23)17-6-4-15(5-7-17)12-21(32)25(36)37;/h1-11,13-14,21,24H,12,32H2,(H,36,37)(H2,33,34,35);1H/t21-,24?;/m0./s1 |
CAS Number | 1040526-12-2 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Off-white solid to white solid |
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Purity | >98% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |