LY-3475070
Catalog No: 21244
CAS Number: 2375815-63-5
Purity: 98% Min.
LY-3475070 is a potent and selective CD73 Inhibitor with IC50 of 28 nM. LY3475070 Alone or in Combination With Pembrolizumab is now under trials for patients with Advanced Cancer.
For research use only. We do not sell to patients.
Chemical Information
| Name | LY-3475070 |
|---|---|
| Iupac Chemical Name | 5-(5-((1S,2R)-2-isopropylcyclopropyl)-6-methylpyridazin-3-yl)pyrimidine-2,4(1H,3H)-dione |
| Synonyms | LY-3475070; LY 3475070; LY3475070; |
| Molecular Formula | C15H18N4O2 |
| Molecular Weight | 286.335 |
| Smile | O=C1NC(C(C2=NN=C(C)C([C@@H]3[C@@H](C(C)C)C3)=C2)=CN1)=O |
| InChiKey | WHRUIISQCORGKK-KOLCDFICSA-N |
| InChi | InChI=1S/C15H18N4O2/c1-7(2)9-4-11(9)10-5-13(19-18-8(10)3)12-6-16-15(21)17-14(12)20/h5-7,9,11H,4H2,1-3H3,(H2,16,17,20,21)/t9-,11+/m1/s1 |
| CAS Number | 2375815-63-5 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% Min. |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
