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LY2228820

Catalog No: 122509
CAS Number: 862507-23-1
Purity: 98% 

LY2228820 is a novel and potent p38MAPK inhibitor (the IC50 for p38MAPK and p38MAPK were 7 nM and 3 nM, respectively). 

For research use only. We do not sell to patients.

Chemical Information

NameLY2228820
Iupac Chemical Name5-[2-tert-butyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-3-(2,2-dimethylpropyl)imidazo[4,5-b]pyridin-2-amine;methanesulfonic acid 
SynonymsRalimetinib dimesylate; LY2228820 dimesylate; LY2228820 2MsOH; LY 2228820; LY-2228820 
Molecular FormulaC26H37FN6O6S2 
Molecular Weight612.737 
SmileCC(C)(C)CN1C2=C(C=CC(=N2)C3=C(N=C(N3)C(C)(C)C)C4=CC=C(C=C4)F)N=C1N.CS(=O)(=O)O.CS(=O)(=O)O
InChiKeyNARMJPIBAXVUIE-UHFFFAOYSA-N
InChiInChI=1S/C24H29FN6.2CH4O3S/c1-23(2,3)13-31-20-17(28-22(31)26)12-11-16(27-20)19-18(14-7-9-15(25)10-8-14)29-21(30-19)24(4,5)6;2*1-5(2,3)4/h7-12H,13H2,1-6H3,(H2,26,28)(H,29,30);2*1H3,(H,2,3,4)
CAS Number862507-23-1
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Ordering Information

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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

122509 - LY2228820 | CAS 862507-23-1

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