LY294002 is the first synthetic molecule known to inhibit PI3K// with IC50 of 0.5 M/0.57 M/0.97 M, respectively; more stable in solution than Wortmannin, and also blocks autophagosome formation.
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Name | LY294002 |
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Iupac Chemical Name | 2-morpholino-8-phenyl-4H-chromen-4-one |
Synonyms | N/A |
Molecular Formula | C19H17NO3 |
Molecular Weight | 307.34 |
Smile | O1CCN(CC1)C=1OC2=C(C=CC=C2C(C1)=O)C1=CC=CC=C1 |
InChiKey | CZQHHVNHHHRRDU-UHFFFAOYSA-N |
InChi | InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2 |
CAS Number | 154447-36-6 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Purity | 98% |
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Storage | 3 years -20ºCpowder 6 months-80ºCin solvent |
Handling | |
HS Code |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |