LY3023414
Catalog No: 611808
CAS Number: 1386874-06-1
Purity: 98%
LY3023414 is an oral ATP competitive inhibitor of the class I PI3K isoforms, mTOR and DNA-PK, extracted from patent WO/2012097039A1, compound example 1, has an IC50 of 64.9 nM, 42.1 nM, 10.6 nM, 19.1 nM for Akt1(pT308), Akt1 (pS473), P70S6(pT389), S6RP(pS240/242).
For research use only. We do not sell to patients.
Chemical Information
| Name | LY3023414 |
|---|---|
| Iupac Chemical Name | (S)-8-(5-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-(2-methoxypropyl)-3-methyl-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one |
| Synonyms | LY3023414; LY-3023414; LY 3023414. |
| Molecular Formula | C23H26N4O3 |
| Molecular Weight | 406.48 |
| Smile | OC(C)(C)C=1C=C(C=NC1)C1=CC=2C3=C(C=NC2C=C1)N(C(N3C[C@H](C)OC)=O)C |
| InChiKey | ACCFLVVUVBJNGT-AWEZNQCLSA-N |
| InChi | InChI=1S/C23H26N4O3/c1-14(30-5)13-27-21-18-9-15(16-8-17(11-24-10-16)23(2,3)29)6-7-19(18)25-12-20(21)26(4)22(27)28/h6-12,14,29H,13H2,1-5H3/t14-/m0/s1 |
| CAS Number | 1386874-06-1 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
