Lenvatinib, also known as E7080, is a synthetic, orally available inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR/FLK-1) tyrosine kinase with potential antineoplastic activity.
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Chemical Information
Name Lenvatinib (E7080)
Iupac Chemical Name 1-(4-(6-carbamoyl-7-methoxyquinolin-4-yloxy)-2-chlorophenyl)-3-cyclopropylurea
Synonyms N/A
Molecular Formula C21H19ClN4O4
Molecular Weight 426.85
Smile C(N)(=O)C=1C=C2C(=CC=NC2=CC1OC)OC1=CC(=C(C=C1)NC(=O)NC1CC1)Cl
InChiKey WOSKHXYHFSIKNG-UHFFFAOYSA-N
InChi InChI=1S/C21H19ClN4O4/c1-29-19-10-17-13(9-14(19)20(23)27)18(6-7-24-17)30-12-4-5-16(15(22)8-12)26-21(28)25-11-2-3-11/h4-11H,2-3H2,1H3,(H2,23,27)(H2,25,26,28)
CAS Number 417716-92-8
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Ordering Information
Packaging Price Availability Purity Shipping Time
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Formulation off-white solid
Purity 98%
Storage 3 years -20ºCpowder
Solubility 5mg/ml in DMSO
Handling
Shipping Condition Shipped under ambient temperature
HS Code
Targets
Mechanism
Cell study
Animal study
Clinical study