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MD-43

Catalog No: 25016
CAS Number:
Purity: ≧98.0%

MD-43 is a potent and selective degrader of MCT4.

For research use only. We do not sell to patients.

Chemical Information

NameMD-43
Iupac Chemical Name2-((1-(2-chlorophenyl)-5-(3-cyclopropoxyphenyl)-1H-pyrazol-3-yl)methoxy)-N-(17-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12,15-pentaoxaheptadecyl)-2-methylpropanamide
SynonymsMD-43 ; MD 43 ; MD43
Molecular FormulaC48H57ClN6O12
Molecular Weight945.46
SmileCC(C)(OCC1=NN(C2=CC=CC=C2Cl)C(C3=CC=CC(OC4CC4)=C3)=C1)C (NCCOCCOCCOCCOCCOCCNC5=CC=CC(C(N6C(CC7)C(NC7=O)=O)=O)=C5C6=O)=O
InChiKeyNFDCDENHIZCMOK-UHFFFAOYSA-N
InChiInChI=1S/C48H57ClN6O12/c1-48(2,66-31-33-30-41(55(53-33)39-12-4-3-10-37(39)49)32-7-5-8-35(29-32)67-34-13-14-34)47(60)51-18-20-62-22-24-64-26-28-65-27-25-63-23-21-61-19-17-50-38-11-6-9-36-43(38)46(59)54(45(36)58)40-15-16-42(56)52-44(40)57/h3-12,29-30,34,40,50H,13-28,31H2,1-2H3, (H,51,60)(H,52,56,57)
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Ordering Information

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FormulationYellow solid
Purity≧98.0%
StorageDry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
SolubilitySoluble in DMSO (DMSO : ≥ 100 mg/mL)
HandlingRefer to MSDS
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
HS Code2934200090
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

25016 - MD-43

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