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MK-0822

Catalog No: 101915
CAS Number: 603139-19-1
Purity: 98% 

MK-0822 is an inhibitor of cathepsin K with potential anti-osteoporotic activity. It selectively binds to and inhibits the activity of cathepsin K, which may result in a reduction in bone resorption, improvement of bone mineral density, and a reversal in osteoporotic changes.
 

For research use only. We do not sell to patients.

Chemical Information

NameMK-0822
Iupac Chemical Name(S)-N-(1-cyanocyclopropyl)-4-fluoro-4-methyl-2-(((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)ethyl)amino)pentanamide 
SynonymsOdanacatib 
Molecular FormulaC25H27F4N3O3S 
Molecular Weight525.56 
SmileC(#N)C1(CC1)NC([C@H](CC(C)(C)F)N[C@H](C(F)(F)F)C1=CC=C(C=C1)C1=CC=C(C=C1)S(=O)(=O)C)=O
InChiKeyFWIVDMJALNEADT-SFTDATJTSA-N
InChiInChI=1S/C25H27F4N3O3S/c1-23(2,26)14-20(22(33)32-24(15-30)12-13-24)31-21(25(27,28)29)18-6-4-16(5-7-18)17-8-10-19(11-9-17)36(3,34)35/h4-11,20-21,31H,12-14H2,1-3H3,(H,32,33)/t20-,21-/m0/s1
CAS Number603139-19-1
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Ordering Information

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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

101915 - MK-0822 | CAS 603139-19-1

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