MK-571 sodium salt
Catalog No: 16123055
CAS Number: 115104-28-4
Purity: 98%
MK-571 is a selective, orally active CysLT1 receptor antagonist. It blocks the binding of LTD4, but not LTC4, to human and guinea pig lung membranes with Ki values of 0.22 nM and 2.1 nM, respectively. MK-571 attenuates kidney ischemia and reperfusion-induced airway hypersensitivity in rats. MK-571 alters bronchoalveolar lavage fluid proteome in a mouse asthma model.
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Chemical Information
| Name | MK-571 sodium salt |
|---|---|
| Iupac Chemical Name | MK-571 sodium salt |
| Synonyms | MK-571; MK 571; MK571; MK-571 sodium salt; L-660,711; L660,711; L 660,711; L-660711; L660711; L 660711. |
| Molecular Formula | C26H26ClN2NaO3S2 |
| Molecular Weight | |
| Smile | CN(C)C(=O)CCSC(c1cccc(c1)/C=C/c2ccc3ccc(cc3n2)Cl)SCCC(=O)[O-].[Na+] |
| InChiKey | XNAYQOBPAXEYLI-AAGWESIMSA-M |
| InChi | InChI=1S/C26H27ClN2O3S2.Na/c1-29(2)24(30)12-14-33-26(34-15-13-25(31)32)20-5-3-4-18(16-20)6-10-22-11-8-19-7-9-21(27)17-23(19)28-22;/h3-11,16-17,26H,12-15H2,1-2H3,(H,31,32);/q;+1/p-1/b10-6+; |
| CAS Number | 115104-28-4 |
| MDL | MFCD00878420 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
