ML224(NCGC00242364; ANTAG3) is a selective TSHR inverse agonist; inhibits TSH-stimulated cAMP production with an IC50 = 2.3 M.
ANTAG3 was selective for TSHR inhibition; half-maximal inhibitory doses were 2.1 M for TSHR and greater than 30 M for LH and FSH receptors .
For research use only. We do not sell to patients.
Name | ML224 |
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Iupac Chemical Name | ML224 |
Synonyms | NCGC00242364; ANTAG3; ML-224 |
Molecular Formula | 1338824-21-7 |
Molecular Weight | 525.59 |
InChiKey | |
InChi | |
CAS Number | 1338824-21-7 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | crystalline solid |
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Purity | 98% |
Storage | 3 years -20ºCpowder |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |