ML311, also known as EU-5346, is a potent and selective inhibitor of the Protein-Protein Interaction of Mcl-1 and Bim. ML311 Potently and Selectively Disrupts the Protein-Protein Interaction of Mcl-1 and Bim.
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Chemical Information
Name ML311
Iupac Chemical Name 7-[(4-Ethylpiperazin-1-yl)-[4-(trifluoromethyl)phenyl]methyl]quinolin-8-ol
Synonyms ML311; ML-311; ML 311; EU-5346; EU 5346; EU5346.
Molecular Formula C23H24F3N3O
Molecular Weight 415.4602
Smile C(C)N1CCN(CC1)C(C1=CC=C2C=CC=NC2=C1O)C1=CC=C(C=C1)C(F)(F)F
InChiKey NGAPBLRRJSKIRT-UHFFFAOYSA-N
InChi InChI=1S/C23H24F3N3O/c1-2-28-12-14-29(15-13-28)21(17-5-8-18(9-6-17)23(24,25)26)19-10-7-16-4-3-11-27-20(16)22(19)30/h3-11,21,30H,2,12-15H2,1H3
CAS Number 315698-17-0
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Ordering Information
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Formulation off-white solid
Purity 98.0%
Storage -20 ℃ for 3 years
Solubility Soluble in DMSO
Handling
Shipping Condition Shipped under ambient temperature
HS Code
Targets
Mechanism
Cell study
Animal study
Clinical study