MMAD
Catalog No: 20179132
CAS Number: 203849-91-6
Purity: 98.0%
MMAD, also known as Monomethyl auristatin D, is a highly potent Tubulin inhibitor. MMAD is one of the auristatins, which are used as the drugs of antibody drug conjugates(ADCs).
For research use only. We do not sell to patients.
Chemical Information
| Name | MMAD |
|---|---|
| Iupac Chemical Name | (S)-N-((3R,4S,5S)-3-methoxy-1-((S)-2-((1R,2R)-1-methoxy-2-methyl-3-oxo-3-(((S)-2-phenyl-1-(thiazol-2-yl)ethyl)amino)propyl)pyrrolidin-1-yl)-5-methyl-1-oxoheptan-4-yl)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamide |
| Synonyms | MMAD, Demethyldolastatin 10; Monomethylauristatin D; Monomethyl Dolastatin 10. |
| Molecular Formula | C41H66N6O6S |
| Molecular Weight | 771.075 |
| Smile | CO[C@H](CC(=O)N1[C@@H](CCC1)[C@@H]([C@H](C(N[C@@H](CC1=CC=CC=C1)C=1SC=CN1)=O)C)OC)[C@H]([C@H](CC)C)N(C([C@H](C(C)C)NC([C@H](C(C)C)NC)=O)=O)C |
| InChiKey | BLUGYPPOFIHFJS-UUFHNPECSA-N |
| InChi | InChI=1S/C41H66N6O6S/c1-12-27(6)36(46(9)41(51)35(26(4)5)45-39(50)34(42-8)25(2)3)32(52-10)24-33(48)47-21-16-19-31(47)37(53-11)28(7)38(49)44-30(40-43-20-22-54-40)23-29-17-14-13-15-18-29/h13-15,17-18,20,22,25-28,30-32,34-37,42H,12,16,19,21,23-24H2,1-11H3,(H,44,49)(H,45,50)/t27-,28+,30-,31-,32+,34-,35-,36-,37+/m0/s1 |
| CAS Number | 203849-91-6 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98.0% |
| Storage | -20 ℃ for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
