Mivebresib
Catalog No: 16123052
CAS Number: 1445993-26-9
Purity: 98%
Mivebresib, also known as ABBV-075, is a potent BET inhibitor (bromodomain (BRD)-containing proteind) with potential antineoplastic activity. Upon administration, the bromodomain inhibitor ABBV-075 binds to the acetyl-lysine binding site in the BRD of certain BRD-containing protein(s), thereby preventing the interaction between those proteins and acetylated histones. This disrupts chromatin remodeling, prevents the expression of certain growth-promoting genes, and leads to an inhibition of cell growth in susceptible tumors.
For research use only. We do not sell to patients.
Chemical Information
| Name | Mivebresib |
|---|---|
| Iupac Chemical Name | N-(4-(2,4-difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide |
| Synonyms | ABBV-075; ABBV 075; ABBV075 |
| Molecular Formula | C22H19F2N3O4S |
| Molecular Weight | 459.4678 |
| Smile | FC1=C(OC2=C(C=C(C=C2)NS(=O)(=O)CC)C=2C3=C(C(N(C2)C)=O)NC=C3)C=CC(=C1)F |
| InChiKey | RDONXGFGWSSFMY-UHFFFAOYSA-N |
| InChi | InChI=1S/C22H19F2N3O4S/c1-3-32(29,30)26-14-5-7-19(31-20-6-4-13(23)10-18(20)24)16(11-14)17-12-27(2)22(28)21-15(17)8-9-25-21/h4-12,25-26H,3H2,1-2H3 |
| CAS Number | 1445993-26-9 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
