Motesanib Diphosphate (AMG-706)
Catalog No: 52101
CAS Number: 857876-30-3
Purity: 98%
Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively; similar activity against Kit, ~10-fold more selective for VEGFR than PDGFR and Ret. Phase 3
For research use only. We do not sell to patients.
Chemical Information
| Name | Motesanib Diphosphate (AMG-706) |
|---|---|
| Iupac Chemical Name | 3-Pyridinecarboxamide, N-(2,3-dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-, phosphate (1:2) |
| Synonyms | AMG-706; Motesanib; AMG706; AMG 706 |
| Molecular Formula | C22H23N5O.2H3PO4 |
| Molecular Weight | 569.44 |
| Smile | CC1(CNc2c1ccc(c2)NC(=O)c3cccnc3NCc4ccncc4)C.OP(=O)(O)O.OP(=O)(O)O |
| InChiKey | ONDPWWDPQDCQNJ-UHFFFAOYSA-N |
| InChi | InChI=1S/C22H23N5O.2H3O4P/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15;2*1-5(2,3)4/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28);2*(H3,1,2,3,4) |
| CAS Number | 857876-30-3 |
| MDL | MFCD12407403 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Purity | 98% |
|---|---|
| Storage | 3 years -20ºCpowder |
| Solubility | 5mg/ml in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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