NCT-501
Catalog No: 16071414
CAS Number: 1802088-50-1
Purity: 98% by HPLC
NCT-501 is a potent ALDH1A1 inhibitor. Aldehyde dehydrogenases (ALDHs) metabolize reactive aldehydes and possess important physiological and toxicological functions in areas such as CNS, metabolic disorders, and cancers. Increased ALDH (e.g., ALDH1A1) gene expression and catalytic activity are vital biomarkers in a number of malignancies and cancer stem cells, highlighting the need for the identification and development of small molecule ALDH inhibitors.
For research use only. We do not sell to patients.
Chemical Information
| Name | NCT-501 |
|---|---|
| Iupac Chemical Name | 8-((4-(cyclopropanecarbonyl)piperazin-1-yl)methyl)-7-isopentyl-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione |
| Synonyms | NCT-501; NCT501; |
| Molecular Formula | C21H32N6O3 |
| Molecular Weight | 416.53 |
| Smile | C1(CC1)C(=O)N1CCN(CC1)CC1=NC=2N(C(N(C(C2N1CCC(C)C)=O)C)=O)C |
| InChiKey | FSXIBBYWVGWQJL-UHFFFAOYSA-N |
| InChi | InChI=1S/C21H32N6O3/c1-14(2)7-8-27-16(22-18-17(27)20(29)24(4)21(30)23(18)3)13-25-9-11-26(12-10-25)19(28)15-5-6-15/h14-15H,5-13H2,1-4H3 |
| CAS Number | 1802088-50-1 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% by HPLC |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
