NMS-293 is a PARP-1 inhibitor in early clinical development at Nerviano Medical Sciences for the treatment of advanced or metastatic solid tumors, including diffuse glioma and glioblastoma.
For research use only. We do not sell to patients.
Name | NMS-293 ( NMS-P293 ) |
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Iupac Chemical Name | 2-(1-cyclohexylpiperidin-4-yl)-3-oxoisoindoline-4-carboxamide |
Synonyms | NMS-03305293 ; NMS-293 ; NMS-P293 ; NMS293 ; NMS 293 |
Molecular Formula | C20H27N3O2 |
Molecular Weight | 341.46 |
Smile | O=C(C1=CC=CC(CN2C3CCN(C4CCCCC4)CC3)=C1C2=O)N |
InChiKey | QBKPYKWJSWOHNY-UHFFFAOYSA-N |
InChi | InChI=1S/C20H27N3O2/c21-19(24)17-8-4-5-14-13-23(20(25)18(14)17)16-9-11-22(12-10-16)15-6-2-1-3-7-15/h4-5,8,15-16H,1-3,6-7,9-13H2,(H2,21,24) |
CAS Number | 1606996-12-6 |
Related CAS | 1606996-12-6 |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Off-white solid |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | PARP-1 Inhibitor |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |