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NU6300

Catalog No: 611923
CAS Number: 2070015-09-5
Purity: 98% 

NU6300 is a non-covalent ATP-competitive CDK2 inhibitor (IC50 = 0.16 mM). 


NU6300 is a covalent CDK2 inhibitor that illustrates the potential of using vinyl sulfones to mediate irreversible inhibition. NU6300 blocks the inhibitor binding site. The effect was time dependent and relatively slow, with less than 50% reduction of the apparent binding capacity in 20 hr.



 

For research use only. We do not sell to patients.

Chemical Information

NameNU6300
Iupac Chemical NameNU6300 
SynonymsNU-6300 
Molecular FormulaC20H23N5O3S 
Molecular Weight413.49 
SmileC[Si](C)(C)CSCCl
InChiKeyIKWIERSJEROYFH-UHFFFAOYSA-N
InChiInChI=1S/C5H13ClSSi/c1-8(2,3)5-7-4-6/h4-5H2,1-3H3
CAS Number2070015-09-5
MDLMFCD17013410
Related CAS

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

611923 - NU6300 | CAS 2070015-09-5

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