NVP-BEP800, also known as BEP-800, is a novel, fully synthetic, orally bioavailable inhibitor that binds to the NH(2)-terminal ATP-binding pocket of Hsp90.
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Chemical Information
Name NVP-BEP800
Iupac Chemical Name 2-amino-4-(2,4-dichloro-5-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-N-ethylthieno[2,3-d]pyrimidine-6-carboxamide
Synonyms NVP BEP800; NVP-BEP 800; NVP BEP-800; BEP-800; BEP800; BEP 800
Molecular Formula C21H23Cl2N5O2S
Molecular Weight 480.41062
Smile NC=1N=C(C2=C(N1)SC(=C2)C(=O)NCC)C2=C(C=C(C(=C2)OCCN2CCCC2)Cl)Cl
InChiKey WJUNQSYQHHIVFX-UHFFFAOYSA-N
InChi InChI=1S/C21H23Cl2N5O2S/c1-2-25-19(29)17-10-13-18(26-21(24)27-20(13)31-17)12-9-16(15(23)11-14(12)22)30-8-7-28-5-3-4-6-28/h9-11H,2-8H2,1H3,(H,25,29)(H2,24,26,27)
CAS Number 847559-80-2
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Ordering Information
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Formulation off-white solid
Purity 98%
Storage 3 years -20ºCpowder
Solubility Soluble in DMSO
Handling
Shipping Condition Shipped under ambient temperature as non-hazardous chemical.
HS Code
Targets
Mechanism
Cell study
Animal study
Clinical study