NXP800 is an oral small molecule inhibitor of the Heat Shock Factor 1 (HSF1) pathway. NXP800 may advance ovarian clear cell carcinoma (OCCC) and relapse/refractory endometrioid ovarian cancer, which are both serious conditions of unmet medical need.
For research use only. We do not sell to patients.
Name | NXP-800 ( CCT361814 ) |
---|---|
Iupac Chemical Name | N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamido)-2-fluorophenyl)-2-((4-ethylpiperazin-1-yl)methyl)quinoline-6-carboxamide |
Synonyms | NXP-800; NXP 800 ; NXP800 ; CCT361814 ; CCT 361814 ; CCT-361814 |
Molecular Formula | C32H32FN5O4 |
Molecular Weight | 569.63 |
Smile | O=C(C1=CC=C2N=C(CN3CCN(CC)CC3)C=CC2=C1)NC4=CC(NC(C5=CC=C(OCCO6)C6=C5)=O)=CC=C4F |
InChiKey | UBALMDIKIGDHJW-UHFFFAOYSA-N |
InChi | InChI=1S/C32H32FN5O4/c1-2-37-11-13-38(14-12-37)20-25-6-3-21-17-22(4-9-27(21)34-25)32(40)36-28-19-24(7-8-26(28)33)35-31(39)23-5-10-29-30(18-23)42-16-15-41-29/h3-10,17-19H,2,11-16,20H2,1H3,(H,35,39)(H,36,40) |
CAS Number | 1693734-80-3 |
Related CAS | 1693734-80-3 |
Packaging | Price | Availability | Purity | Shipping Time |
---|---|---|---|---|
Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Yellow solid |
---|---|
Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | |
---|---|
Mechanism | |
Cell study | |
Animal study | |
Clinical study |