Napabucasin
Catalog No: 16122708
CAS Number: 83280-65-3
Purity: 98%
Napabucasin is an orally available Stat3 and cancer cell stemness inhibitor.Napabucasin downregulates stemness gene expression driven by Stat3 and cancer stemness properties, and effectively inhibits self-renewal of stemness-high cancer cells with IC50 ranged from 0.291~1.19 M, on inhibition on normal stem cells.
For research use only. We do not sell to patients.
Chemical Information
| Name | Napabucasin |
|---|---|
| Iupac Chemical Name | 2-Acetylnaphtho[2,3-b]furan-4,9-dione |
| Synonyms | BBI608; BBI 608; BB-I608; Napabucasin |
| Molecular Formula | C14H8O4 |
| Molecular Weight | 240.21 |
| Smile | C(C)(=O)C1=CC2=C(O1)C(C1=CC=CC=C1C2=O)=O |
| InChiKey | DPHUWDIXHNQOSY-UHFFFAOYSA-N |
| InChi | InChI=1S/C14H8O4/c1-7(15)11-6-10-12(16)8-4-2-3-5-9(8)13(17)14(10)18-11/h2-6H,1H3 |
| CAS Number | 83280-65-3 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
