Nazartinib (EGF816)
Catalog No: 1781004
CAS Number: 1508250-71-2
Purity: 98.0%
Nazartinib, also known as EGF816, is an orally available, irreversible, third-generation, mutant-selective epidermal growth factor receptor (EGFR) inhibitor, with potential antineoplastic activity.
For research use only. We do not sell to patients.
Chemical Information
| Name | Nazartinib (EGF816) |
|---|---|
| Iupac Chemical Name | (R,E)-N-(7-chloro-1-(1-(4-(dimethylamino)but-2-enoyl)azepan-3-yl)-1H-benzo[d]imidazol-2-yl)-2-methylisonicotinamide |
| Synonyms | EGF816;EGF-816;EGF 816;Nazartinib |
| Molecular Formula | C26H31ClN6O2 |
| Molecular Weight | 495.02 |
| Smile | ClC1=CC=CC2=C1N(C(=N2)NC(C2=CC(=NC=C2)C)=O)[C@H]2CN(CCCC2)C(\C=C\CN(C)C)=O |
| InChiKey | IOMMMLWIABWRKL-WUTDNEBXSA-N |
| InChi | InChI=1S/C26H31ClN6O2/c1-18-16-19(12-13-28-18)25(35)30-26-29-22-10-6-9-21(27)24(22)33(26)20-8-4-5-15-32(17-20)23(34)11-7-14-31(2)3/h6-7,9-13,16,20H,4-5,8,14-15,17H2,1-3H3,(H,29,30,35)/b11-7+/t20-/m1/s1 |
| CAS Number | 1508250-71-2 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98.0% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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