Noscapine HCl
Catalog No: 17022711
CAS Number: 912-60-7
Purity: 98%
Noscapine, also known as Narcotine, Nectodon, Nospen, Anarcotine and (archaic) Opiane, is a benzylisoquinoline alkaloid from plants of the poppy family, without painkilling properties. This agent is primarily used for its antitussive (cough-suppressing) effects. Noscapine's antitussive effects appear to be primarily mediated by its ҨCreceptor agonist activity. Evidence for this mechanism is suggested by experimental evidence in rats. Pretreatment with rimcazole, a -specific antagonist, causes a dose-dependent reduction in antitussive activity of noscapine. Noscapine, and its synthetic derivatives called noscapinoids, are known to interact with microtubules and inhibit cancer cell proliferation
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Chemical Information
| Name | Noscapine HCl |
|---|---|
| Iupac Chemical Name | Noscapine HCl |
| Synonyms | Noscapine Hydrochloride; Narcotine, Nectodon, Nospen, Anarcotine and (archaic) Opiane |
| Molecular Formula | C22H24ClNO7 |
| Molecular Weight | 449.884 |
| Smile | CN1CCc2cc3c(c(c2[C@@H]1[C@@H]4c5ccc(c(c5C(=O)O4)OC)OC)OC)OCO3.Cl |
| InChiKey | MFLVZFXCSKVCSH-URBRKQAFSA-N |
| InChi | InChI=1S/C22H23NO7.ClH/c1-23-8-7-11-9-14-20(29-10-28-14)21(27-4)15(11)17(23)18-12-5-6-13(25-2)19(26-3)16(12)22(24)30-18;/h5-6,9,17-18H,7-8,10H2,1-4H3;1H/t17-,18+;/m1./s1 |
| CAS Number | 912-60-7 |
| MDL | MFCD00082546 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
