OATD-02, an orally available dual arginase inhibitor (ARG1 and ARG2), is in phase I clinical development at Molecure for the treatment of patients with advanced and/or metastatic solid tumors, including colorectal cancer, ovarian cancer, pancreatic cancer or renal cell carcinoma.
For research use only. We do not sell to patients.
Name | OATD-02 |
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Iupac Chemical Name | (1R,2S,5R)-1-amino-5-(2-boronoethyl)-2-((dimethylamino)methyl)cyclohexane-1-carboxylic acid |
Synonyms | OATD-02 ; OATD 02 ; OATD02 |
Molecular Formula | C12H25BN2O4 |
Molecular Weight | 272.15 |
Smile | O=C([C@]1(N)[C@H](CN(C)C)CC[C@@H](CCB(O)O)C1)O |
InChiKey | NZNAXQBYXLSQHO-JBLDHEPKSA-N |
InChi | InChI=1S/C12H25BN2O4/c1-15(2)8-10-4-3-9(5-6-13(18)19)7-12(10,14)11(16)17/h9-10,18-19H,3-8,14H2,1-2H3,(H,16,17)/t9-,10-,12+/m0/s1 |
CAS Number | 2146132-73-0 |
Related CAS | 2146132-73-0 |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |