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ONX-0914 ( PR-957 )

Catalog No: 52013
CAS Number: 960374-59-8
Purity: ≧95.0%

ONX-0914, an inhibitor of the LMP7 and LMP2 subunits of immunoproteasomes, has activity in multiple models of autoimmune diseases.

For research use only. We do not sell to patients.

Chemical Information

NameONX-0914 ( PR-957 )
Iupac Chemical Name(S)-3-(4-methoxyphenyl)-N-((S)-1-((R)-2-methyloxiran-2-yl)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)propanamido)propanamide
SynonymsONX 0914 ; ONX0914 ; ONX-0914 ; PR957 ; PR-957 ; PR 957
Molecular FormulaC31H40N4O7 
Molecular Weight580.67 
SmileN1(CCOCC1)CC(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=C(C=C1)OC)C(=O)N[C@H](C(=O)[C@@]1(OC1)C)CC1=CC=CC=C1
InChiKeyWQAVPPWWLLVGFK-VTNASVEKSA-N
InChiInChI=1S/C31H40N4O7/c1-21(32-27(36)19-35-13-15-41-16-14-35)29(38)34-26(18-23-9-11-24(40-3)12-10-23)30(39)33-25(28(37)31(2)20-42-31)17-22-7-5-4-6-8-22/h4-12,21,25-26H,13-20H2,1-3H3,(H,32,36)(H,33,39)(H,34,38)/t21-,25-,26-,31+/m0/s1
CAS Number960374-59-8
Related CAS960374-59-8

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
BulkEnquiryEnquiryEnquiry
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Formulationoff-white solid 
Purity≧95.0%
StorageDry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
SolubilitySoluble in DMSO
HandlingAvoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
HS Code2934200090
Coming soon.
Targets LMP7 and LMP2 inhibitor
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

52013 - ONX-0914 ( PR-957 ) | CAS 960374-59-8

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