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Oclacitinib

Catalog No: 16122705
CAS Number: 1640292-55-2
Purity: 98% 

Oclacitinib is a novel inhibitor of JAK family members with IC50 ranging from 10 to 99 nM and JAK1-dependent cytokines with IC50 ranging from 36 to 249 nM, which did not inhibit a panel of 38 non-JAK kinases. PF-03394197 is most potent at inhibiting JAK1. PF-03394197 also inhibits the function of JAK1-dependent cytokines involved in allergy and inflammation as well as pruritus. PF-03394197 has minimal effects on cytokines which does not activate the JAK1 enzyme in cells 

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Chemical Information

NameOclacitinib
Iupac Chemical NameOclacitinib 
SynonymsPF-03394197 
Molecular FormulaC15H23N5O2S.C4H4O4 
Molecular Weight453.51 
InChiKey
InChi
CAS Number1640292-55-2
Related CAS

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

16122705 - Oclacitinib | CAS 1640292-55-2

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