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Osimertinib mesylate

Catalog No: 1712154
CAS Number: 1421373-66-1
Purity: >98%

Osimertinib,也被称为Mereletinib和AZD- 9291,是第三代EGFR抑制剂,为晚期肺癌患者在临床研究前带来了希望,这些晚期肺癌已经对现有的EGFR抑制剂产生了耐药性。

For research use only. We do not sell to patients.

Chemical Information

NameOsimertinib mesylate
Iupac Chemical NameN-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide mesylate
SynonymsAZD-9291; AZD 9291; AZD9291; AZD-9291 mesylate; Mereletinib; Mereletinib mesylate; Osimertinib mesylate.
Molecular FormulaC29H37N7O5S
Molecular Weight595.72
SmileCN(CCN(C)C)C1=CC(OC)=C(C=C1NC(C=C)=O)NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2.OS(=O)(C)=O
InChiKeyFUKSNUHSJBTCFJ-UHFFFAOYSA-N
InChiInChI=1S/C28H33N7O2.CH4O3S/c1-7-27(36)30-22-16-23(26(37-6)17-25(22)34(4)15-14-33(2)3)32-28-29-13-12-21(31-28)20-18-35(5)24-11-9-8-10-19(20)24;1-5(2,3)4/h7-13,16-18H,1,14-15H2,2-6H3,(H,30,36)(H,29,31,32);1H3,(H,2,3,4)
CAS Number1421373-66-1
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Formulation浅黄色粉末
Purity>98%
Storage短期可在0-4度保存,数天至数月;长期可在-20度保存三年。
Solubility可溶于DMSO
Handling
Shipping Condition可在常温下运输
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

1712154 - Osimertinib mesylate | CAS 1421373-66-1

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