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Oxolinic acid

Catalog No: 16122720
CAS Number: 14698-29-4
Purity: 98% 

Oxolinic acid is a quinolone antibiotic, inhibiting the enzyme DNA gyrase and DNA synthesis.It also acts as a dopamine reuptake inhibitor.Oxolinic acid, a quinolone antibacterial agent, inhibits reversibly the ATP-dependent replicative DNA synthesis in permeable cell systems as well as in cellophane disk lysates[4]. It also inhibits bacterial DNA gyrase but not eukaryotic topoisomerases, reversibly binding gyrase subunit A in gyrase-DNA complexes, blocking supercoiling activity and inhibiting DNA synthesis at 0.5-5 g/ml 

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Chemical Information

NameOxolinic acid
Iupac Chemical NameOxolinic acid 
SynonymsUrinox, NSC 110364 
Molecular FormulaC13H11NO5 
Molecular Weight261.23 
SmileCCN1C=C(C(=O)C=2C1=CC1=C(C2)OCO1)C(=O)O
InChiKeyKYGZCKSPAKDVKC-UHFFFAOYSA-N
InChiInChI=1S/C13H11NO5/c1-2-14-5-8(13(16)17)12(15)7-3-10-11(4-9(7)14)19-6-18-10/h3-5H,2,6H2,1H3,(H,16,17)
CAS Number14698-29-4
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Ordering Information

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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
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Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

16122720 - Oxolinic acid | CAS 14698-29-4

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