PBT434, also known as ATH434 , is a novel, brain-penetrant, inhibitor of α-synuclein aggregation.
For research use only. We do not sell to patients.
Name | PBT434 Hydrobromide |
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Iupac Chemical Name | 5,7-dichloro-2-((ethylamino)methyl)-8-hydroxy-3-methylquinazolin-4(3H)-one hydrobromide |
Synonyms | PBT434 Hydrobromide ; PBT 434 ; PBT-434 ; PBT434 ; ATH434 ; ATH-434 ; ATH 434 ; |
Molecular Formula | C12H14BrCl2N3O2 |
Molecular Weight | 383.07 |
Smile | O=C1N(C(CNCC)=NC2=C1C(Cl)=CC(Cl)=C2O)C.[H]Br |
InChiKey | WNTSHYWJAPIRQE-UHFFFAOYSA-N |
InChi | InChI=1S/C12H13Cl2N3O2.BrH/c1-3-15-5-8-16-10-9(12(19)17(8)2)6(13)4-7(14)11(10)18;/h4,15,18H,3,5H2,1-2H3;1H |
CAS Number | 1232841-78-9 |
Related CAS | 1232841-78-9 |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Off-white solid |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | inhibitor of α-synuclein aggregation |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |