PCI-27483
Catalog No: 110401
CAS Number: 871266-63-6
Purity: 98%
PCI-27483 is a reversible small-molecule inhibitor of activated factor VII (factor VIIa) with potential antineoplastic and antithrombotic activities. FVII, a serine protease, becomes activated (FVIIa) upon binding with TF forming the FVIIa/TF complex, which induces intracellular signaling pathways by activating protease activated receptor 2.
For research use only. We do not sell to patients.
Chemical Information
| Name | PCI-27483 |
|---|---|
| Iupac Chemical Name | (S)-2-(2-(5-(5-carbamimidoyl-1H-benzo[d]imidazol-2-yl)-2',6-dihydroxy-5'-sulfamoyl-[1,1'-biphenyl]-3-yl)acetamido)succinic acid |
| Synonyms | PCI27483; PCI 27483 |
| Molecular Formula | C26H24N6O9S |
| Molecular Weight | 596.569 |
| Smile | C1=CC2=C(C=C1C(=N)N)NC(=C3C=C(C=C(C3=O)C4=C(C=CC(=C4)S(=O)(=O)N)O)CC(=O)NC(CC(=O)O)C(=O)O)N2 |
| InChiKey | PVTVTDSZGJFYRP-UHFFFAOYSA-N |
| InChi | InChI=1S/C26H24N6O9S/c27-24(28)12-1-3-17-18(8-12)32-25(31-17)16-6-11(7-21(34)30-19(26(38)39)10-22(35)36)5-15(23(16)37)14-9-13(42(29,40)41)2-4-20(14)33/h1-6,8-9,19,31-33H,7,10H2,(H3,27,28)(H,30,34)(H,35,36)(H,38,39)(H2,29,40,41) |
| CAS Number | 871266-63-6 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
