PD-159206 is a nucleocapsid inhibitor. It exhibits good antiviral activity against HIV.
For research use only. We do not sell to patients.
Name | PD-159206 |
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Iupac Chemical Name | 2,2'-((2,2'-disulfanediylbis(benzoyl))bis(azanediyl))bis(3-methylpentanoic acid) |
Synonyms | PD-159206; PD159206; PD 159206; |
Molecular Formula | C26H32N2O6S2 |
Molecular Weight | 532.67 |
Smile | O=C(NC(C(C)CC)C(O)=O)C1=CC=CC=C1SSC2=CC=CC=C2C(NC(C(C)CC)C(O)=O)=O |
InChiKey | SUQDXZBTWJQATJ-UHFFFAOYSA-N |
InChi | InChI=1S/C26H32N2O6S2/c1-5-15(3)21(25(31)32)27-23(29)17-11-7-9-13-19(17)35-36-20-14-10-8-12-18(20)24(30)28-22(26(33)34)16(4)6-2/h7-16,21-22H,5-6H2,1-4H3,(H,27,29)(H,28,30)(H,31,32)(H,33,34) |
CAS Number | 171744-42-6 |
Related CAS | 171744-42-6 |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Off-white solid |
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Purity | ≧94.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |
1: Sharmeen L, McQuade T, Heldsinger A, Gogliotti R, Domagala J, Gracheck S. Inhibition of the early phase of HIV replication by an isothiazolone, PD 161374. Antiviral Res. 2001 Feb;49(2):101-14. doi: 10.1016/s0166-3542(00)00143-1. PMID: 11248362.
2: Domagala JM, Gogliotti R, Sanchez JP, Stier MA, Musa K, Song Y, Loo J, Reily M, Tummino P, Harvey P, Hupe D, Sharmeen L, Mack D, Scholten J, Saunders J, McQuade T. 2,2'-Dithiobisbenzamides and 2-benzisothiazolones, two new classes of antiretroviral agents: SAR and mechanistic considerations. Drug Des Discov. 1997 May;15(1):49-61. PMID: 9332831.