PD153035 Hcl is a potent and specific inhibitor of EGFR with Ki and IC50 of 5.2 pM and 29 pM; little effect against PGDFR, FGFR, CSF-1, InsR and Src.
For research use only. We do not sell to patients.
Chemical Information
Name | PD153035 Hcl |
Iupac Chemical Name | N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine;hydrochloride |
Synonyms | ZM 252868; AG 1517; Tyrphostin AG 1517; SU 5271; PD-153035; PD 153035 |
Molecular Formula | C16H15BrClN3O2 |
Molecular Weight | 396.666 |
Smile | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC.Cl |
InChiKey | ZJOKWAWPAPMNIM-UHFFFAOYSA-N |
InChi | InChI=1S/C16H14BrN3O2.ClH/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11;/h3-9H,1-2H3,(H,18,19,20);1H |
CAS Number | 183322-45-4 |
Related CAS | |
Ordering Information
Packaging | Price | Availability | Purity | Shipping Time |
Bulk | | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
Purity | 98% |
Storage | -20 ºC for 3 years |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code | |
Targets | |
Mechanism | |
Cell study | |
Animal study | |
Clinical study | |