PD 158780 is a potent in vitro inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) (IC50 0.08 nM).
For research use only. We do not sell to patients.
Name | PD 158780 |
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Iupac Chemical Name | 4-N-(3-bromophenyl)-6-N-methylpyrido[3,4-d]pyrimidine-4,6-diamine |
Synonyms | PD 158780; PD158780; PD-158780. |
Molecular Formula | C14H12BrN5 |
Molecular Weight | 330.19 |
Smile | CNC1=CC2=C(NC3=CC=CC(Br)=C3)N=CN=C2C=N1 |
InChiKey | KFHMLBXBRCITHF-UHFFFAOYSA-N |
InChi | InChI=1S/C14H12BrN5/c1-16-13-6-11-12(7-17-13)18-8-19-14(11)20-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,16,17)(H,18,19,20) |
CAS Number | 171179-06-9 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | off-white solid |
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Purity | >98% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |