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PE859

Catalog No: 185157
CAS Number: 1402727-29-0
Purity: >98%

PE859 is a potent inhibitor of both tau and Aβ aggregation with IC50 values of 0.66 and 1.2 μM, respectively.

For research use only. We do not sell to patients.

Chemical Information

NamePE859
Iupac Chemical Name6-((E)-2-(5-((E)-2-methoxy-4-(pyridin-2-ylmethoxy)styryl)-1H-pyrazol-3-yl)vinyl)-1H-indole
SynonymsPE859; PE-859; PE 859.
Molecular FormulaC28H24N4O2
Molecular Weight448.526
SmileCOC1=CC(OCC2=NC=CC=C2)=CC=C1/C=C/C3=CC(/C=C/C4=CC5=C(C=C4)C=CN5)=NN3
InChiKeyAMBZHNVCLPHAKA-NSJFVGFPSA-N
InChiInChI=1S/C28H24N4O2/c1-33-28-18-26(34-19-25-4-2-3-14-29-25)12-9-22(28)8-11-24-17-23(31-32-24)10-6-20-5-7-21-13-15-30-27(21)16-20/h2-18,30H,19H2,1H3,(H,31,32)/b10-6+,11-8+
CAS Number1402727-29-0
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationOff-white solid to white solid
Purity>98%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

185157 - PE859 | CAS 1402727-29-0

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