Ritlecitinib ( PF-06651600 )
Catalog No: 18435
CAS Number: 1792180-81-4
Purity: ≧98.0%
Ritlecitinib ( PF-06651600 ) is a potent and selective JAK3 inhibitor. PF-06651600, a potent and low clearance compound with demonstrated in vivo efficacy.
For research use only. We do not sell to patients.
Chemical Information
| Name | Ritlecitinib ( PF-06651600 ) |
|---|---|
| Iupac Chemical Name | 1-((2S,5R)-5-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one |
| Synonyms | PF-06651600 ; PF 06651600 ; PF06651600 ; Ritlecitinib |
| Molecular Formula | C15H19N5O |
| Molecular Weight | 285.34 |
| Smile | C=CC(N1[C@@H](C)CC[C@@H](NC2=C3C(NC=C3)=NC=N2)C1)=O |
| InChiKey | CBRJPFGIXUFMTM-WDEREUQCSA-N |
| InChi | InChI=1S/C15H19N5O/c1-3-13(21)20-8-11(5-4-10(20)2)19-15-12-6-7-16-14(12)17-9-18-15/h3,6-7,9-11H,1,4-5,8H2,2H3,(H2,16,17,18,19)/t10-,11+/m0/s1 |
| CAS Number | 1792180-81-4 |
| Related CAS | 1792180-81-4 (free base) 2140301-97-7 (malonate) |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid to white solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Handling | Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation. |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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