PF-0684000, also known as EOS200271, is potent IDO-1 inhibitor (IC50 0.15 μM). PF-0684000 has moderate hIDO1 enzyme inhibition (IC50 0.41 μM).
For research use only. We do not sell to patients.
Name | PF-0684000 |
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Iupac Chemical Name | 3‑(5-Fluoro‑1H‑indol-3-yl)pyrrolidine-2,5-dione |
Synonyms | EOS200271, EOS-200271; EOS 200271; PF-0684000; PF 06840003; PF06840003. |
Molecular Formula | C12H9FN2O2 |
Molecular Weight | 232.2144 |
Smile | O=C(C(C1=CNC2=C1C=C(F)C=C2)C3)NC3=O |
InChiKey | MXKLDYKORJEOPR-UHFFFAOYSA-N |
InChi | InChI=1S/C12H9FN2O2/c13-6-1-2-10-7(3-6)9(5-14-10)8-4-11(16)15-12(8)17/h1-3,5,8,14H,4H2,(H,15,16,17) |
CAS Number | 198474-05-4 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Off-white solid to white solid |
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Purity | >98% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |