PF-562271, also known as PF-562,271 and PF-271, is an orally bioavailable small molecule and ATP-competitive focal adhesion kinase (FAK) inhibitor with potential antineoplastic and antiangiogenic activities.
For research use only. We do not sell to patients.
Name | PF-562271 HCl |
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Iupac Chemical Name | N-methyl-N-(3-(((2-((2-oxoindolin-5-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)methyl)pyridin-2-yl)methanesulfonamide hydrochloride |
Synonyms | PF562271; PF562271; PF-562271; PF562,271. |
Molecular Formula | C21H21ClF3N7O3S |
Molecular Weight | 543.9502 |
Smile | CS(=O)(N(C)C1=NC=CC=C1CNC2=NC(NC3=CC4=C(NC(C4)=O)C=C3)=NC=C2C(F)(F)F)=O.[H]Cl |
InChiKey | RQEBZJWSAAWCAV-UHFFFAOYSA-N |
InChi | InChI=1S/C21H20F3N7O3S.ClH/c1-31(35(2,33)34)19-12(4-3-7-25-19)10-26-18-15(21(22,23)24)11-27-20(30-18)28-14-5-6-16-13(8-14)9-17(32)29-16;/h3-8,11H,9-10H2,1-2H3,(H,29,32)(H2,26,27,28,30);1H |
CAS Number | 939791-41-0 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Formulation | off-white solid |
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Purity | >98% |
Storage | 3 years -20ºCpowder |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
HS Code |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |