PF-CBP1, also known as PF-06670910, is potent and highly-selective inhibitor of the bromodomain of CREB binding protein (CBP BRD) that down regulates targets of CBP in macrophages primary neurons.
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Chemical Information
Name PF-CBP1 free base
Iupac Chemical Name 4-(2-(5-(3,5-Dimethylisoxazol-4-yl)-2-(4-propoxyphenethyl)-1H-benzo[d]imidazol-1-yl)ethyl)morpholine
Synonyms PF-CBP1; PF-CBP-1; PF-CBP 1; PF-06670910; PF 06670910; PF06670910.
Molecular Formula C29H36N4O3
Molecular Weight 488.632
Smile CC1=NOC(=C1C1=CC2=C(N(C(=N2)CCC2=CC=C(C=C2)OCCC)CCN2CCOCC2)C=C1)C
InChiKey CGWBJJZOKGZCSJ-UHFFFAOYSA-N
InChi InChI=1S/C29H36N4O3/c1-4-17-35-25-9-5-23(6-10-25)7-12-28-30-26-20-24(29-21(2)31-36-22(29)3)8-11-27(26)33(28)14-13-32-15-18-34-19-16-32/h5-6,8-11,20H,4,7,12-19H2,1-3H3
CAS Number 1962928-21-7
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Ordering Information
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Formulation off-white solid
Purity 98.0%
Storage -20 ℃ for 3 years
Solubility Soluble in DMSO
Handling
Shipping Condition Shipped under ambient temperature
HS Code
Targets
Mechanism
Cell study
Animal study
Clinical study