PF-06447475 is a highly potent, selective, brain penetrant LRRK2 inhibitor with IC0 of 3 nM/11 nM for Wt LRRK2/G2019S LRRK2 respectively.
For research use only. We do not sell to patients.
Chemical Information
Name | PF06447475 |
Iupac Chemical Name | 3-(4-morpholino-7H-pyrrolo[2,3-d]pyrimidin-5-yl)benzonitrile |
Synonyms | PF-06447475; PF 06447475; PF6447475; PF-6447475; PF 6447475 |
Molecular Formula | C17H15N5O |
Molecular Weight | 305.33 |
Smile | N#CC1=CC=CC(C2=CNC3=NC=NC(N4CCOCC4)=C32)=C1 |
InChiKey | BHTWDJBVZQBRKP-UHFFFAOYSA-N |
InChi | InChI=1S/C17H15N5O/c18-9-12-2-1-3-13(8-12)14-10-19-16-15(14)17(21-11-20-16)22-4-6-23-7-5-22/h1-3,8,10-11H,4-7H2,(H,19,20,21) |
CAS Number | 1527473-33-1 |
Related CAS | |
Ordering Information
Packaging | Price | Availability | Purity | Shipping Time |
Bulk | | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
Purity | 98% |
Storage | -20 ºC for 3 years |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code | |
Targets | |
Mechanism | |
Cell study | |
Animal study | |
Clinical study | |